Danemarca – Echipament biomedical – PacBio Vega System og reagenser

PacBio Vega System og reagenser til long-read sekventering Klagenævnet for Udbud PacBio Vega System og reagenser Frivillig forudgående bekendtgørelse (udbudslovens § 80, offentlig kontrakt): Klage under stand still: Kontrakten kan ikke indgås før udløbet af 10 kalenderdage regnet fra dagen efter den dag, hvor nærværende bekendtgørelsen er offentliggjort. Klage efter indgået kontrakt: 45 kalenderdage efter at ordregiveren har offentliggjort en bekendtgørelse i Den Europæiske Unions Tidende om, at ordregiveren har indgået en kontrakt. Konkurrence- og forbrugerstyrelsen Mercell Holding ASA Specification for sequencing technology: The Capital Region intends to purchase a Vega™ system from Pacific Bio-sciences of California, Inc. (PacBio) for long-read sequencing. The instrument is to be placed at the Department of Pathology, Herlev Hospital. The technology will be used for clinical longread sequencing on formalin fixed paraffin fixed tissue of tumor samples. The reason for choosing Vega™ from PacBio for this purpose is that the Vega™ system is the only system on the marked which fulfills ALL our requirements for a system for clinical longread sequencing, as described in the following: 1) It is required that the system can be implemented into our existing infrastructure. PacBio Vega™ fulfills this requirement because it is compatible with automation on Tecan liquid handlers and can be in-tegrated in our existing setup for data infrastructure. In addition, li-braries can be prepared for sequencing on the system from rela-tively low DNA input material, i.e., from < 1 µg to low-µg range, repair multiple DNA damaged, amplification-free, and still result in high data quality, thereby making the system usable for our clinical samples, also with limited DNA amount, thereby, being compatible with our existing workflow. 2) It is required that the system can measure DNA methylation at CpG sites during the sequencing run, without additionally use of chemical requirement. 3) It is required that system results in high enough data quality to support the use of longread as a stand-alone analysis, thereby eventu-ally enabling the technology to replace selected existing analyses. PacBio Vega™ is the sole system to fulfill this requirement because their circular sequencing technology (PacBio Single Molecule Real-Time SMRT® sequencing) generates precise reads of 750–1,500 base pairs with at least 90% of bases >Q30 on FFPE tissue samples. Furthermore, detection of small variants (SNVs/indels), structural variants (SVs), repeat expansions, methylation at CpG sites and haplotype phasing happens from a single library and sequencing run, generating simultaneous SNVs (>99.9% F1), indels (>99.3% F1) and structural variants (>95% F1) calling, thereby supporting the use of the method as stand-alone method. PacBio Vega™ is the sole system who has developed a robust HiFi sequencing of FFPE tissue samples. 4) It is required that the sequencing data should be processed with as low compute and low data storage as possible on the marked to re-duce costs for CPU and storage on our existing data infrastructure (HPC). PacBio is the only sequencing technology to offer HiFi reads, which support both high accuracy and low compute, data storage, and data transfer requirements due to the efficient representation of the HiFi read file format. Furthermore, the PacBio system provides an option for accurate primary and secondary analysis using soft-ware pipelines specifically designed to analyze HiFi long reads. Region Hovedstaden Afdeling for Patologi Herlev Hospital Borgmester Ib Juuls Vej 73 Opgang 7, 4. etage, L5 2730 Herlev Fast pris Pacific Biosciences DNK https://eu.eu-supply.com/ctm/company/companyinformation/index/66963 01 Askekroken 11 [email eliminat] none Kongens Vænge 2 d6594cfb-aaf7-49d2-8777-528dbe8ef6fb-01 [telefon eliminat] [telefon eliminat] supplies price 8800 other-exclusive FiscalDocID1 Viborg 1303 O'Brien Drive DK042 12:14:05+00:00 CON-0001 ra 0 32014L[telefon eliminat] can-standard fix-tot 2000-01-01Z 179/2026 37795526 94025 29 TEN-0001 eforms-sdk-1.13 RES-0001 Nævnenes Hus, Toldboden 2 2026-09-16+02:00 ••• ••• 00 Pernille Nielsen USA complainants 488de6eb-2546-469f-9507-39a67b86e77c 980921565 health https://www.regionh.dk/ [email eliminat] 33124110 DAN 0277 2730 2.3 38000000 ted-esen 2026-09-15+00:00 ••• ••• 19 neg-wo-call selec-w DK013 DK012 2500 Hillerød ORG-0003 ORG-0004 ORG-0005 12:30:46+00:00 ORG-0001 ORG-0002 Oslo DKK [telefon eliminat] NO081 Herlev no-eu-funds NOR true 38434540 ENG eSender no [email eliminat] http://mercell.com/ medium http://www.klfu.dk EnvDocID1 200419240 Borgmester Ib Juuls vej 73 LOT-[telefon eliminat] TPA-0001 http://www.kfst.dk 4700010796 USA Federal Tax Identification No. 16-1590339 29190623 8393cef2-8720-4c12-b645-ab802946c13a false Carl Jacobsens Vej 35 Menlo Park, Calefornia [telefon eliminat] [email eliminat] 26056049 Valby 100 [telefon eliminat] tenders 38434000 | Klagenaevnet for Tender The pathology department Herlev Hospital The Capital Region of Denmark Specification for sequencing technology: The Capital Region intends to purchase a Vega™ system from Pacific Bio-sciences of California, Inc. (PacBio) for long-read sequencing. The instrument is to be placed at the Department of Pathology, Herlev Hospital. The technology will be used for clinical longread sequencing on formalin fixed paraffin fixed tissue of tumor samples. The reason for choosing Vega™ from PacBio for this purpose is that the Vega™ system is the only system on the marked which fulfills ALL our requirements for a system for clinical longread sequencing, as described in the following: 1) It is required that the system can be implemented into our existing infrastructure. PacBio Vega™ fulfills this requirement because it is compatible with automation on Tecan liquid handlers and can be integrated in our existing setup for data infrastructure. In addition, li-braries can be prepared for sequencing on the system from relatively low DNA input material, i.e., from < 1 µg to low-µg range, repair multiple DNA damaged, amplification-free, and still result in high data quality, thereby making the system usable for our clinical samples, also with limited DNA amount, thereby, being compatible with our existing workflow. 2) It is required that the system can measure DNA methylation at CpG sites during the sequencing run, without additionally use of chemical requirement. 3) It is required that system results in high enough data quality to sup-port the use of longread as a stand-alone analysis, thereby eventually enabling the technology to replace selected existing analyses. PacBio Vega™ is the sole system to fulfill this requirement because their circular sequencing technology (PacBio Single Molecule Real-Time SMRT® sequencing) generates precise reads of 750–1,500 base pairs with at least 90% of bases >Q30 on FFPE tissue samples. Furthermore, detection of small variants (SNVs/indels), structural variants (SVs), repeat expansions, methylation at CpG sites and haplotype phasing happens from a single library and sequencing run, generating simultaneous SNVs (>99.9% F1), indels (>99.3% F1) and structural variants (>95% F1) calling, thereby supporting the use of the method as stand-alone method. PacBio Vega™ is the sole system who has developed a robust HiFi sequencing of FFPE tissue samples. 4) It is required that the sequencing data should be processed with as low compute and low data storage as possible on the marked to re-duce costs for CPU and storage on our existing data infrastructure (HPC). PacBio is the only sequencing technology to offer HiFi reads, which support both high accuracy and low compute, data storage, and data transfer requirements due to the efficient representation of the HiFi read file format. Furthermore, the PacBio system provides an option for accurate primary and secondary analysis using software pipelines specifically designed to analyze HiFi long reads. PacBio Vega System and reagents Mercell Holding ASA fast pris Voluntary ex ante transparency notice (Section 80 of the Public Procurement Act, public contract): Complaint during the standstill period: The contract may not be concluded before the expiry of 10 calendar days calculated from the day following the date of publication of this notice. Complaint after contract conclusion: 45 calendar days after the contracting authority has published a notice in the Official Journal of the European Union stating that the contracting authority has concluded a contract. Region Hovedstaden long-read sequencing DNK https://eu.eu-supply.com/ctm/company/companyinformation/index/66963 01 Askekroken 11 [email eliminat] none Kongens Vænge 2 d6594cfb-aaf7-49d2-8777-528dbe8ef6fb-01 [telefon eliminat] [telefon eliminat] supplies price 8800 other-exclusive FiscalDocID1 Viborg 1303 O'Brien Drive DK042 12:14:05+00:00 CON-0001 ra 0 32014L[telefon eliminat] can-standard fix-tot 2000-01-01Z 179/2026 37795526 94025 29 TEN-0001 eforms-sdk-1.13 RES-0001 Nævnenes Hus, Toldboden 2 2026-09-16+02:00 ••• ••• 00 Pernille Nielsen USA complainants 488de6eb-2546-469f-9507-39a67b86e77c 980921565 health https://www.regionh.dk/ [email eliminat] 33124110 DAN 0277 2730 2.3 38000000 ted-esen 2026-09-15+00:00 ••• ••• 19 neg-wo-call selec-w DK013 DK012 2500 Hillerød ORG-0003 ORG-0004 ORG-0005 12:30:46+00:00 ORG-0001 ORG-0002 Oslo DKK [telefon eliminat] NO081 Herlev no-eu-funds NOR true 38434540 ENG eSender no [email eliminat] http://mercell.com/ medium http://www.klfu.dk EnvDocID1 200419240 Borgmester Ib Juuls vej 73 LOT-[telefon eliminat] TPA-0001 http://www.kfst.dk 4700010796 USA Federal Tax Identification No. 16-1590339 29190623 8393cef2-8720-4c12-b645-ab802946c13a false Carl Jacobsens Vej 35 Menlo Park, Calefornia [telefon eliminat] [email eliminat] 26056049 Valby 100 [telefon eliminat] tenders 38434000