Danemarca – Spectrometre de masă – Orbital Tribrid APEX og Orbitrap Astral Zoom

Kontrakt om levering af to massespektrometre mv. Thermo Fisher Scientific is the only economic operator capable of supplying the complete required configuration comprising one Orbitrap Astral Zoom, one Orbitrap Tribrid APEX, two FAIMS Pro Duo interfaces, and two Vanquish Neo UHPLC systems. The Orbitrap Astral Zoom and Orbitrap Tribrid APEX are proprietary mass-spectrometry platforms developed, manufactured, and sold exclusively by Thermo Fisher Scientific. The specific combination of technologies incorporated into these systems—including the Orbitrap mass analyzer, Astral analyzer, Tribrid architecture, FAIMS Pro Duo interface, and IR-laser-enabled fragmentation—is unique to Thermo Fisher Scientific and is not available from any other manufacturer. The two mass spectrometers are not interchangeable but provide complementary capabilities required for PRI’s scientific activities and proteomics services. Orbitrap Astral Zoom The Orbitrap Astral Zoom combines a high-selectivity quadrupole mass filter, a high-resolution Orbitrap analyzer, and the proprietary Astral analyzer within one instrument. While the Orbitrap analyzer provides high-resolution, accurate-mass full-scan analysis with resolution settings of up to 480,000 FWHM at m/z 200, the Astral analyzer provides ultrafast, high-resolution MS/MS acquisition at rates of up to 270 Hz. The parallelized instrument architecture provides the acquisition speed, sensitivity, mass resolution, and quantitative performance required for: • narrow-window data-independent acquisition; • high-throughput analysis using short LC gradients; • large-cohort plasma and tissue proteomics; • low-input and single-cell proteomics; • deep proteome coverage at throughputs of up to 300 samples per day; and • multiplexed quantitative proteomics using TMTpro reagents. Other manufacturers offer high-performance mass spectrometers suitable for individual proteomics applications. However, no other supplier offers an instrument that combines an Orbitrap analyzer with the proprietary Astral analyzer and provides an equivalent combination of acquisition speed, mass resolution, sensitivity, ion-processing parallelization, and compatibility with PRI’s established Orbitrap Astral workflows. Orbitrap Tribrid APEX The Orbitrap Tribrid APEX provides advanced analytical capabilities that cannot be delivered by the Orbitrap Astral Zoom. Its proprietary Tribrid architecture combines quadrupole precursor selection, ion-trap analysis, high-resolution Orbitrap detection, extensive ion-processing parallelization, and multistage MSⁿ acquisition within a single instrument. The required APEX configuration additionally provides: • synchronous precursor selection MS³; • real-time library searching and adaptive acquisition; • collision-induced dissociation; • higher-energy collisional dissociation; • electron-transfer dissociation; • electron-transfer/higher-energy collision dissociation; and • IR-laser-enabled activation and infrared multiphoton dissociation. These complementary fragmentation and acquisition capabilities are required for advanced TMTpro multiplexed quantification, targeted TMT workflows, glycoproteomics, cross-linking mass spectrometry, immunopeptidomics, detailed characterization and localization of post-translational modifications, and structural and top-down proteomics. In particular, synchronous precursor selection MS³ is required to reduce reporter-ion interference and improve quantitative accuracy in complex TMTpro experiments. Real-time library searching and adaptive acquisition enable detected peptides to be identified during acquisition and directed into targeted confirmatory experiments. ETD and EThcD enable peptide-backbone fragmentation while preserving labile post-translational modifications, improving peptide-sequence coverage and modification-site localization. The integrated IR laser further expands the available fragmentation and structural-proteomics workflows and improves reporter-ion generation in multiplexed quantitative experiments. Although other suppliers offer high-performance mass spectrometers capable of addressing some of these applications, no alternative supplier offers the required combination of Orbitrap detection, Tribrid MSⁿ architecture, SPS-MS³, real-time adaptive acquisition, ETD/EThcD, and integrated IR-laser-enabled fragmentation. Københavns Universitet Klagenævnet for Udbud Thermo Electron A/S Kan ikke opdeles efter sit indhold Orbital Tribrid APEX og Orbitrap Astral Zoom The contract can be provided only by a particular economic operator who can comply with the set requirements. Mercell Holding ASA The Proteomics Research Infrastructure (PRI), University of Copenhagen, intends to acquire the following integrated LC–MS instrumentation: • one Thermo Scientific Orbitrap Astral Zoom mass spectrometer; • one Thermo Scientific Orbitrap Tribrid APEX mass spectrometer; • two Thermo Scientific FAIMS Pro Duo interfaces; and • two Thermo Scientific Vanquish Neo UHPLC systems. The purchase includes the associated ion sources, software, installation, integration, training, and service components I henhold til lov om Klagenævnet for Udbud gælder følgende frist for indgivelse af klage: Senest samtidig med at en klage indgives til Klagenævnet for Udbud, skal klageren skriftligt underrette ordregiveren om, at klage indgives til Klagenævnet for Udbud, og om, hvorvidt klagen er indgivet i den periode på 10 kalenderdage, som er fastsat i § 4, stk. 1, nr. 2. I tilfælde, hvor klagen ikke er indgivet i denne periode, skal klageren tillige angive, hvorvidt der begæres opsættende virkning af klagen, jf. § 12, stk. 1. Herefter klagefrist på 30 kalenderdage for klage over en ordregivers beslutning om, at ordregiveren har til hensigt at indgå kontrakt med en bestemt virksomhed og har anvendt proceduren i § 4. Klagefristen løber fra offentliggørelsen af bekendtgørelse om indgåelse af kontrakt, jf. § 7, stk. 3. Konkurrence- og Forbrugerstyrelsen DNK 01 education [telefon eliminat] Askekroken 11 [email eliminat] https://www.thermofisher.com/dk/en/home.html none https://www.kfst.dk [telefon eliminat] [telefon eliminat] supplies København K 8800 Nørregade 10 a083034c-b88f-4cf3-bd5e-15a993ab46c2 Viborg DK041 CON-0001 quality 0 32014L0024 1 per-exa 2 can-standard Allerød http://www.ku.dk/ 2000-01-01Z 2026-09-09Z https://naevneneshus.dk/start-din-klage/klagenaevnet-for-udbud/ body-pl 37795526 2026-09-23Z 04 ••• ••• 29 TEN-0001 eforms-sdk-1.13 RES-0001 Nævnenes Hus, Toldboden 2 2200 [email eliminat] 38433100 complainants 980921565 [email eliminat] DAN 0277 Carl Jacobsens vej 35 2.3 ted-esen 10294819 92c98c0a-3303-4aba-99e5-8d886e667a85-01 neg-wo-call selec-w DK011 14:01:05+00:00 DK013 t-med DK012 2500 189/2026 ORG-0003 ORG-0004 ORG-0005 13:43:02+00:00 0431-0068/26-7000 ORG-0001 ORG-0002 Oslo [telefon eliminat] DKK [telefon eliminat] NO081 2026-09-28+00:00 3450 no-eu-funds NOR 8532615.03 https://eu.eu-supply.com/ctm/company/companyinformation/index/166597 true eSender no technical 1165 http://mercell.com/ medium LOT-0000 DK28314388 Blegdamsvej 3B TPA-0001 CPQ-00904920 københavn N false [email eliminat] Tina Marie Møller c47a667e-3f6e-4edd-99f5-cb02cf0f99c1 Valby 100 [telefon eliminat]+02:00